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Our team

Our team brings together trainees, clinicians, and microbiologists to
study the airway microbiome in cystic fibrosis and bronchiectasis.

Lab members

Current Members

Christina Thornton
Principal Investigator

Christina Thornton, MD, PhD, FRCPC

Dr. Thornton is a clinician scientist specializing in cystic fibrosis and bronchiectasis. Her PhD thesis (under the supervision of Dr. Michael Surette) looked at the lower respiratory microbiome and microbial interactions in cystic fibrosis patients. She completed her internal medicine residency followed by respirology fellowship at the University of Calgary in 2021. Dr. Thornton then went on to the University of Michigan (under the supervision of Drs. John LiPuma and Lindsay Caverly) where she completed a postdoctoral fellowship in advanced microbiome community analysis in cystic fibrosis patients. She is now an assistant professor as of Aug 2022 at the University of Calgary. Dr. Thornton runs a research lab with key interests around the role of polymicrobial infections at times of clinical stability and pulmonary exacerbation in suppurative lung disease including bronchiectasis and cystic fibrosis.

Swathi Purighalla
Lab Manager

Swathi Purighalla, MSc

Swathi completed her undergraduate degree at the University of Calgary and, after completion, entered her M.Sc. program in Microbiology studying cystic fibrosis lung infections under the supervision of Dr. Douglas Storey, also at the U of C. She then worked as a Clinical Scientist in the Infection Control and Prevention team at a hospital in India for over 5 years. After taking time off to raise her daughter, she joined The Hospital for Sick Children, Toronto, as a Clinical Reseach Coordinator working on a Phase II clinical trial. Swathi joined Christina’s lab in 2023 as Lab Manager, performing a range of duties and developing the Canadian Bronchiectasis Clinical Database.

Atena Sadat Sombolestani
Postdoctoral Associate

Atena Sadat Sombolestani, PhD

Atena completed her bachelor’s and master’s degrees in microbiology at the University of Isfahan, Iran. During this time, she focused on applied microbiology, particularly on the use of acetic acid bacteria as probiotics. She was then awarded a special research scholarship (BOF) from Ghent University, where she earned her Ph.D. in Biochemistry and Biotechnology in Belgium. Her doctoral research focused on the taxonomy and genomics of bacteria. In addition, she investigated the potential health benefits of homemade kombucha by analyzing its microbiome and metabolite composition. As a postdoctoral researcher, Atena studies the microbiology of wildfire smoke. Her research aims to use this knowledge to unravel the mechanisms by which wildfire smoke exacerbates asthma.

Ariel MacKenzie
PhD Student

Ariel MacKenzie, MSc

Ariel earned her MSc in 2023 investigating colonic mucus and inflammatory responses before working in finance for the International Microbiome Centre. Her PhD work is supported by the Distinguished Doctoral Recruitment Scholarship and the CIHR CGRS-D. In her spare time, she likes to bake, volunteer for the Canadian Cancer Society, and spend time with her two dogs.

Jack Burke-Gaffney
Master's Student

Jack Burke-Gaffney

Jack is a current Master’s student in the Thornton Lab, pursuing a degree in Medical Microbiology and Infectious Disease at the University of Calgary. His research focuses on Candida albicans in the lungs of people with cystic fibrosis, examining how the fungus contributes to pulmonary exacerbations and how it interacts with other microbes, particularly Pseudomonas aeruginosa, within the CF lung environment. His work spans morphological, transcriptional, and functional analyses of clinical isolates to better understand the fungal-bacterial dynamics that drive disease worsening.

Haley Finlay
Assistant

Haley Finlay

Haley supports administrative and research operations across the lab.

Alumni

Shahrbano Rukunuddin
Former Undergraduate Student

Shahrbano Rukunuddin

Shahrbano is a fourth year Bachelor of Health Sciences Student at the University of Calgary. Her current summer project is focused on characterizing the microbiome and mycobiome of Pulmonary Aspergilloma.

Simarpreet Kaur
Master's Student

Simarpreet Kaur, MSc

Simar is a master’s student in the Thornton lab interested in exploring the role of microbiomes in bronchiectasis. Her current project focuses on deciphering the lung microbiome during pulmonary exacerbations and clinical stability in non-cystic fibrosis bronchiectasis. Prior to joining the Thornton lab Simar completed Bachelor of Science in Microbiology from Delhi University and Master of Science in Microbial Biotechnology from Panjab University, India. After completion of her master's degree, she worked as research fellow for four years at Post Graduate Institute of Medical Education and Research, India.

Nicole Boechler
Medical Student

Nicole Boechler

Nicole is currently a medical student in the Cumming School of Medicine’s Class of 2028. She received her Bachelor of Health Sciences (Honours) from the University of Calgary in 2025, and completed her undergraduate thesis under the supervision of Dr. Christina Thornton. Her research explores the microbiological profiles of patients with bronchiectasis, and focuses on outcomes related to small colony variants. Outside of school, Nicole enjoys playing recreational sports and flute, and is always on the lookout for a new place to eat.